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BioWorld Science

June 17, 2002

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Abbott presents new erythromycins with improved GI tolerability

New hydroxamic acids with MMP/TNF-alpha-inhibitory activity from Fujisawa

GSK presents novel inhibitors of IKK-beta

TNF-alpha production inhibitors in early development at Nikken Chemicals

Kissei claims SGLT2 inhibitors for use in diabetes and obesity

New alpha4 integrin-selective cell adhesion inhibitors identified at Japanese lab

Axokine enters study in obese patients with type 2 diabetes

Patient enrollment completed in two DAC:opioid phase II trials

New mechanisms of action reported for Esterom in primary and secondary hyperalgesia

Neurodex completes phase II/III trial in emotional lability

Hypoxic cell cytotoxin licensed to KuDOS

Azapinoindoles with high affinity for the 5-HT2C receptor subtype designed at Pharmacia

Potent analgesic agents emerge from a series of pyrrole alkylamide analogues

Strategies in the development of 5-HT2A-selective antagonists

Safety data for NBI-6024 in adolescent type 1 diabetics support further development

HIM2 examined for systemic pharmacokinetics in dogs, oral absorption in diabetic patients

ADA news: dual PPARalpha/gamma agonist has beneficial effects on glucose, lipids

BMS-298585 exerts both glucose- and lipid-lowering effects in animal models

Procyon updates development of key product candidates

Continued expression of anti-HIV-1 antisense RNA up to 24 months after HGTV-43 gene therapy

InNexus acquires SAT rights to 1F7

AEterna updates Neovastat progress

CpG-7909 enters phase I/II in malignant melanoma

FDA advisory committee sets date to review Vanlev

Novogen initiates second clinical trial of NV-07a

Oncolytics to acquire interest in Transition Therapeutics

Zyprexa approved in E.U. for manic episodes associated with bipolar disorder

Extina enters phase III for seborrheic dermatitis

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