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BioWorld Science

June 26, 2002

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First market introduction for ultrasound imaging agent from Alliance

BioVex commences phase I trial of OncoVEX GM-CSF for solid tumors

Oral retinoid for CTCL introduced in Germany

Potent HDAC inhibitors identified at Abbott with submicromolar antitumor activity

Phase III trial of MorphiDex does not meet study endpoints

Proof of principle for orally active CCKA agonist GI-181771X

First noninvasive cholesterol test receives FDA approval

ENDO 2002 presentations discuss preclinical findings for rexinoid LG-100268

MediGene discontinues development of candidate for heart failure

BVT-2733 tested in three animal models of type 2 diabetes

BIM-51077, a stable GLP-1 analogue, shows potential in the management of type 2 diabetes

Cephalon and TransTech announce research collaboration

Introgen's Advexin receives proprietary name approval from FDA

Texas Biotechnology claims alpha4beta1 antagonists for atherosclerosis and other conditions

Roche and StressGen collaborate to develop drug for HPV-related diseases

Orally available prodrugs of MMP inhibitors presented by Sumitomo

IL-6 production inhibitors identified at Taisho and Sagami

Good safety and efficacy profiles reported for adalimumab in Stockholm

Novel PTP1B inhibitors in early development at Japan Tobacco

Meiji Milk claims compounds with neurotrophic, antioxidant and antitumor activity

Sphingosine kinase inhibitor and its use in restenosis, etc.

More on the gastrointestinal safety of the specific COX-2 inhibitor valdecoxib

Novel antifungal compound isolated from R. lineatus cultures

Etoricoxib a highlight at this year's EULAR meeting

Antiestrogenic effects of Sch-57068 in female reproductive organs examined in detail in rats

Remicade launched in Japan for Crohn's disease

Pegasys approved in E.U.

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