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BioWorld Science

July 11, 2002

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GSK describes ALK5 inhibitors with potential in renal diseases, etc.

The PPAR coagonist LY-465608 reduces progression of atherosclerotic lesions

Ritonavir reported to have antineoplastic effects against Kaposi's sarcoma

FDA approves pivotal periodontal surgery trial of dermal substitute

CIMA announces first European launches of Remeron SolTab

Micrologix and Fujisawa to codevelop and commercialize MBI-226

Promising preclinical and early clinical findings reported this week for RSD-1235 at IUPHAR 2002

Capravirine not associated to date with an increased risk of vasculitis in the clinic

RS-1178 specifically attenuates Abeta-induced macrophage activation

Novel spin-trapping agent shows promise for neurodegenerative disorders

RS-0406 presented as novel beta-sheet breaker with potential in Alzheimer's disease

Alleviation of neuropathic pain demonstrated for NO-releasing gabapentin derivative

GT-015 superior to glyceryl trinitrate in cardioprotective efficacy in isolated rat hearts

Fast-track AIDS drug T-20 highlighted at the 14th International AIDS Conference

Potential role of the combination of orlistat and fluvastatin in obesity

New data on ezetimibe presented at the EAS congress

Potential use of a combination of two recombinant adenoviral vectors in cancer gene therapy

Kyorin patents new immunosuppressant proteasome inhibitors

Novel histamine H3 modulators for AD and other disorders

Bayer PARP inhibitors with potential in ischemia-reperfusion injury

New steroid 17-20 lyase inhibitors identified by Takeda R&D team

Biovitrum presents novel 5-HT2C ligands for use in obesity and other conditions

Selective alphav integrin antagonists in early development at Merck