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BioWorld Science

Sep. 16, 2002

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Factor 5A gene induces apoptosis in human cancer cells

Ionix advances development of intranasal opioid analgesic

INDs filed for M-Vax and O-Vax

Novavax submits Estrasorb NDA

New E.U. approvals sought for Pennsaid

Memantine + donepezil produces benefit in AD patients

NV-04 shows promise in initial phase I study

New Drug Associates licenses lipoprotein remnant targeting technology from U. of Alabama

Medicure seeks strategic alliances for MC-1

Initial stage of HuMax-CD4 phase II trial completes enrollment

Valtrex approved for treatment of cold sores

Clinical results for dutasteride in the treatment of BPH reported at SIU congress

Pharmacokinetics, efficacy and safety of tadalafil discussed at meeting in Stockholm

Sarpogrelate for muscle cramps in hemodialysis patients

Chinese research demonstrates efficacy and safety of epristeride for BPH

Zoledronic acid effective against bone lesions in prostate cancer in late-stage trial

TAK-475: synthesis and preliminary pharmacological profile of a new squalene synthase inhibitor

First dual AT1/ET-A receptor antagonist with oral activity shows promise for hypertension Rx

NO donor inhibits platelet deposition on damaged coronary vessels in pig model

Selective or dual kinase inhibitors covered by Ortho-McNeil patent

New trypsin-like protease inhibitors and their use in thrombosis, cancer, etc.

Lilly claims new sPLA2 inhibitors having potential in sepsis and other inflammatory disorders

Antipsychotic 5-HT2A antagonists patented by Merck

Inhibitors of IL-1beta and TNF-alpha production newly developed at Sankyo

U. of Texas research group discovers new Src kinase inhibitors

Boron-containing modulators of nicotinic alpha7 receptors and their use in CNS disorders

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