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BioWorld Science

Sep. 30, 2002

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HuMax-CD4 does not meet primary endpoint in phase II rheumatoid arthritis trial

ERbeta agonist isolated from plant by Merck researchers

Novel CB2 agonists and their use in pain, glaucoma, epilepsy, etc.

Spanish lab reveals new magnetic resonance contrast agents

UCB acquires Cardiome's antitussive program

Phase I TNFerade trial in soft tissue sarcoma fully enrolled

Tanabe AAI signs development and licensing agreements for first three compounds

Wyeth to evaluate BioVex's NeuroVEX vectors

Bone-targeted Src tyrosine kinase inhibitor may have use in bone metastases

PT-141 shows phase I potential for female sexual dysfunction

Cerebril IND filed for hemorrhagic stroke due to cerebral amyloid angiopathy

Cel-Sci signs agreement for evaluation of CEL-1000 against herpes

Bristol-Myers Squibb to reacquire U.S. copromotion rights for Tequin from Schering-Plough

FeRx regains rights to MTC-DOX following termination of Elan joint venture

Small-molecule inhibitor of RANK-RANKL interaction presented at ASBMR meeting

Preclinical data support use of KRN-1493 in secondary hyperparathyroidism

Potent, selective EP4 agonists identified at Pfizer, effective in osteopenic rat model

AP-23588 exerts both antiresorptive and bone formation-enhancing effects

NNC-55-0118 characterized as beta-cell-selective potassium channel opener

Dong-A selects oxazolidinone DA-7867 as development candidate

Inhibitors of IL-1beta and/or TNF-alpha prepared and tested at Sankyo

BMS identifies 5-HT2 receptor modulators for obesity and other disorders

Biaryl LDL receptor upregulators reported in Takeda patent

NNRTI with potent activity against mutant and wild-type enzymes

Zofimarin-related antifungal agent examined in vitro and in vivo at Sankyo

BMS selects clinical development candidate for RSV infection

Antibacterial activity and toxicity of CP-5609, a new carbapenem, reported at ICAAC

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