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BioWorld Science

Nov. 7, 2002

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Novo Nordisk to use Neose's GlycoPEGylation technology

Sankyo granted option for second-generation gluconeogenesis inhibitor for type 2 diabetes

Two series of peptide deformylase inhibitors reported in GSK patents

Neurogenetics and Eisai enter research agreement in late-onset AD

Pain Therapeutics to initiate pilot program for low-dose opioid antagonist therapy in IBS

Novel inhibitor of 5-HT and noradrenaline reuptake designed at Lilly

Uvidem enters phase II for metastatic melanoma

GSK patent covers new beta2-adrenoceptor agonists with utility in respiratory disorders

Pharmacia synthesizes inhibitors of herpesvirus DNA polymerase

4SC presents novel proteasome inhibitors for use in protozoal infections

Antibacterial fusidic acid derivatives prepared and tested at Leo

Novel HIV RT inhibitors in GSK pipeline

AMPA receptor antagonist E-2007 effective in animal models of epilepsy and MS

Broad-spectrum caspase inhibitor provides protection against neurotoxins in vivo

Lexrite receives phase I SBIR grant from NCI

Two new PARP inhibitors with neuroprotective activity described by Guilford at Neuroscience 2002

Novo Nordisk submits marketing application for insulin detemir

FDA committee recommends approval of Clozaril to treat suicidal behavior

Galileo identifies potent redox metabolic modulator with neuroprotective efficacy

FDA approves new indication for SecreFlo

Procognitive effects of 5-HT6 receptor antagonist determined in animal models

Inhibition of PARP with CEP-6376 provides significant neuroprotection in rat stroke model

SSR-591813: a selective partial nicotinic alpha4beta receptor agonist for nicotine addiction

Dopamine agonist-induced motor complications prevented by KW-6002

OGT-923 enters clinical testing

Ocinaplon produces statistically significant reductions in anxiety in phase II trial

Remodulin approved for pulmonary arterial hypertension in Israel

Schering-Plough obtains marketing rights to Foradil Aerolizer from Novartis

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