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BioWorld Science

Dec. 9, 2002

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Pleiotropic effects of statins: effects on cerebral cholesterol metabolism but not Abeta secretion

ZP-120 completes phase I trial

Genesis Bioventures and Innathera sign letter of intent for proposed business combination

High response rate found for temozolomide plus celecoxib in recurrent malignant glioma

No cytotoxic effect reported for seocalcitol monotherapy in pancreatic cancer

Proof of principle for novel dosing schedule of methylphenidate in ADHD

CeMines and CePeP enter pilot program for peptide-based cancer drugs

Conantokin-L: a new conantokin peptide with NMDA-antagonist and anticonvulsant activity

Antinociceptive activity of FR-143166 involves spinal serotonergic system

Provigil label expanded in U.K.

AP-158 effective against biofilms

Marketing authorization application submitted for Striant in U.K.

Four series of antipsychotic dopamine D2 antagonists identified at Wyeth

Ricerca obtains rights to targets from Lilly's small-molecule antibacterial program

Lilly Icos presents new PDE5 inhibitors for male and female sexual dysfunction

Prolysis and Evotec collaborate on antibiotic discovery

Vertex researchers describe novel series of ERK inhibitors

GSK patent covers novel agents for herpesvirus infections

Novel inhibitors of HRV 2A protease in early development at Iconix

Gilead to acquire Triangle Pharmaceuticals

Synthon successful in its challenge of an SKB patent for paroxetine mesilate

Apoptosis-inducing hydrazones as novel antitumor agents

Once-weekly NeoRecormon approved in Europe for cancer-related anemia

Dendreon announces amended pivotal trial for Provenge prostate cancer vaccine

Phase I trial for BBR-2778 in MS to begin early next year

Corixa and Kirin collaborate on WT1 cancer vaccine development

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