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BioWorld Science

Nov. 19, 2002

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New data on the safety of drotrecogin alfa (activated) in severe sepsis

Aventis claims novel angiotensin(1-7) receptor agonists for angina pectoris and other disorders

New antiproliferative compounds isolated from fungal species

Modulators of estrogen receptors prepared and tested at GSK

Bayer identifies novel thyroid hormone-like compounds with utility in lipoprotein disorders

Ortho-McNeil claims series of histamine H4 antagonists and their use in asthma

Bayer presents novel p38 inhibitors for COPD

Kowa describes compounds with dual antiplatelet/vasodilating activity

Novel analgesic agents in early development at Gruenenthal

Evotec signs medicinal chemistry optimization agreement with British Biotech

U. of British Columbia and ARC sign license agreement for novel antiinflammatories

NIH grant for development of cyanovirin-N to prevent sexual transmission of HIV

Abbott and Domantis form research collaboration

Helsinn grants CJ Corp. license and distribution rights for palonosetron in Korea

Hyseq and Variagenics to merge

GC-C technology has potential as marker and target for gastric and esophageal cancers

New Novartis program to evaluate once-yearly zoledronic acid in osteoporosis

First approval for new antipsychotic drug granted by FDA

Cardiac isoform-selective inhibitor of adenylyl cyclase presented in Chicago

Novel target to prevent heart attacks and strokes discovered at Lexicon

Potential antiarrhythmic agent that predominantly blocks I(Kur) currents in atrium

ENMD-0995 trial for patients with multiple myeloma under way

AtheroGenics awarded CIHR grant for CART-2 atherosclerosis trial

Enrollment completed for BLP25 liposomal vaccine study in non-small cell lung cancer

Selective p38alpha MAPK inhibitor NPC-31145 improves outcome in glomerulonephritis

SMP-534, an orally active TGF-beta inhibitor, shows promise for diabetic renal disease

Effects of DPC-423 in rabbit model suggest clinical utility in preventing arterial thrombosis

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