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BioWorld Science

Jan. 8, 2003

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Genome Therapeutics and Wyeth extend osteoporosis research alliance

Manufacturing and supply agreement signed for Genasense

Metformin XT NDA submitted for type 2 diabetes

Endo submits NDA for extended-release oxymorphone

Zyvox approved for bacterial infections in infants and children

CAT and Xoma enter crosslicensing agreement for antibody technologies

Indevus looks back at fiscal 2002

Potent, nonpeptide CCK1 receptor antagonist developed by Italian scientists

Thiazolidinone CFTR channel inhibitor identified at UCSF

Zovirax approved by FDA for recurrent cold sores

sNDA filed for Seroquel in acute mania associated with bipolar disorder

Enzon and SkyePharma form technology alliance

Additional thielavins identified as glucose-6-phosphatase inhibitors at Pfizer

Celgene completes acquisition of Anthrogenesis

Furin inhibition as a new strategy for controlling infections

Final pivotal phase III trials of AC-2993 complete enrollment

Sosei obtains Japanese rights to Eligard

Medarex files IND for MDX-070

Essential Therapeutics discontinues development of ETRX-101

Excellent oral anticoagulant activity demonstrated for YM-60828 derivative

Vertex to lead development of VX-950 in restructured agreement with Lilly

Lilly designs novel estrogen receptor modulators

Leo claims guanidine-based IKK inhibitors for cancer and inflammatory disorders

Sankyo presents novel sialidase inhibitors with utility in influenza virus infections

Antagonists of migration-inhibitory factor (MIF) discovered at Avanir

New series of NK2/NK3 antagonists and their use reported by Sanofi-Synthelabo

Roche discloses mGluR5 antagonists and their use in anxiety and pain

BMS claims new antagonists of LFA-1 and Mac-1/ICAM interaction

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