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BioWorld Science

Feb. 18, 2003

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Isis reports development highlights for 2002

N-type calcium channel blockers and their use in cerebral ischemia and pain

BMS presents new ACE/NEP inhibitors with potential in hypertension and heart failure

New protein kinase inhibitors covered by Aventis patent

Antitumor antibiotic isolated by Nippon Kayaku scientists

Pyrrolidine-based beta-lactamase inhibitors newly discovered at Banyu

New chemokine receptor modulators in early development at Ono

Merger plans announced by Epimmune and Anosys

Targeted chemotherapy of endometrial and ovarian cancers with cytotoxic LHRH analogue

New orexin-1 receptor antagonists covered by GSK patents

Aventis reaches telithromycin marketing alliance agreement for Japan

Wilex and San Raffaele sign cleaved uPA receptor agreement

Vivus completes treatment in at-home Alista study

Phase III atrasentan study fails to meet primary endpoint in end-stage prostate cancer

LidoPAIN SP produces statistically significant improvement in postoperative pain

IND filed for Oxycyte phase I trials

Introgen to pursue registration plans for Advexin in NSCLC

Boehringer Ingelheim commences PRoFESS study for prevention of second stroke

Single dose of TNX-355 reported to decrease viral load in HIV infection

New data on the antitumor efficacy and toxicity of S-16020-2 in refractory tumors

Pharmacodynamics and pharmacokinetics of infliximab in psoriatic patients

Neuroprotective effects of IL-6 in mice with virus-induced neuronal injury

YC-1 increases the incidence of penile erection in rats

IkB kinase 2: a potential target for prevention of transplant rejection

Histone deacetylase inhibitors block T-cell activity and may prevent allograft rejection

PNA CXCR3 antisense lengthens skin allograft survival in vivo