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BioWorld Science

May 8, 2003

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Kappa opioid receptor antagonist with antidepressant-like effects

First-quarter highlights at Avant

Introgen gains license to fus1 anticancer gene

Progress made in Bexxar review

Shire summarizes R&D highlights for the first quarter

Dry eye symptoms improve after transdermal application of testosterone cream

Extended-release ciprofloxacin in complicated urinary tract infections

Improved retinal thickness found with midostaurin in diabetic macular edema

Tetracyclic 5-HT receptor modulators identified by Pharmacia (Pfizer)

New smooth muscle-selective muscarinic antagonists covered by Kyorin patent

Alpha7 nicotinic agonists with utility in cognition disorders, psychosis, etc.

Tetrazole-based mGluR5 antagonists in early development at Merck

Gedeon Richter presents three series of selective dopamine D3 receptor modulators

Wyeth scientists prepare and test two series of 5-HT6 receptor ligands

Novel helicoidal urea-containing oligomers with antifungal and antibacterial activity

TACE inhibitors, their preparation and use described in Kaken patent

Novartis advances Medarex antibody into clinical development

Updated phase II results for Tocosol Paclitaxel

Schering AG and Astex enter drug discovery collaboration

Neurogenetics licenses phase II compound from Lilly

New Risperdal formulation launched

Inhibitex presents results from first Veronate clinical study

StreptAvax stimulates broad immune response in phase II study

VNS Therapy effective in children with resistant seizures

Rat study suggests potential of topiramate in treating nicotine addiction

Development of memantine for neuropathic pain under review following pivotal results

Kucera reveals anti-HIV small molecule with novel mechanism of action in Savannah

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