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BioWorld Science

May 12, 2003

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Once-monthly octreotide acetate improves visual acuity in cystoid macular edema

Antiviral and antiinflammatory effects for N-chlorotaurine in adenoviral keratoconjunctivitis

Tripep to acquire Isconova

Development of CEL-1000 for herpes simplex funded by NIAID

Initiation of phase I clinical trial of TTS-CD3 in patients with NSCLC

PDL discontinues development of anti-IL-4 antibody for asthma

NeoPharm granted FDA permission for LEP-ETU clinical trial

Xcyte T-cell product enters phase I/II trial in multiple myeloma

Abgenix and Sosei enter CRTH2-targeting antibody development agreement

Genentech and ABC(2) to collaborate on Tarceva brain cancer trial

Dendreon uses telomerase in new cancer immunotherapy

Emisphere's oral insulin candidate enters clinical testing

Vancomycin-cephalosporin conjugates prepared and tested at Theravance

Roche describes another series of adenosine A2A receptor modulators

Tularik reports IRAK inhibitors and their use in inflammatory, proliferative and immune disorders

Dual 5-HT reuptake inhibitors/5-HT1A agonists described in Wyeth patent

Novel H3 receptor modulators designed by Novo Nordisk and Boehringer Ingelheim team

Debio presents new camptothecin prodrugs in recent patent

New PDE5 inhibitors under study at Merck KGaA

Enanta claims new ciclosporin analogues with utility in asthma therapy

Pharmacia (now Pfizer) presents new 5-HT6 receptor ligands

Novartis scientists discover novel steryl sulfatase inhibitors for acne, hirsutism, etc.

Cozaar approved for diabetics with kidney disease and high blood pressure in Canada

Chugai research operations to close in U.S.

Second Merck antibody advances to phase II trials

Licensing opportunity from Milkhaus: ML-04 for BPH and prostatitis

Multivalent Fab molecule targeting ICAM-1 prevents HRV infection

SUN-C8079, a new NF-kB inhibitor, evaluated in vitro and in vivo

New antibacterial agent activated by L-tryptophanase, a bacteria-specific enzyme