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BioWorld - Monday, February 9, 2026
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BioWorld Science
June 11, 2003
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The EP4 agonist Ono-4819 accelerates bone healing in rats
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CGP-41251 demonstrates novel immunosuppressive activity
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Inhibition of p38 MAPK with FR-167653 prevents the onset and progression of arthritis in rats
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D-003 prevents bone loss and reduces bone resorption in ovariectomized rats
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CC-5013 inhibits adhesion molecules and prevents metastasis in an animal model
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Good safety profile for peginterferon alfa-2a in malignant melanoma
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MEDI-522 well tolerated in patients with refractory colorectal cancer
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Pfizer presents promising preclinical data for CP-690550
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Halofuginone efficacy and pharmacokinetic data presented at ASCO
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Evidence of antitumor effects found for endostatin in neuroendocrine tumors
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Once daily NM-3 is well tolerated and has antitumor activity in advanced solid tumors
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ABT-510 is well tolerated and induces antitumor response in cancer patients
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Evaluation of the antiangiogenic effects of chemotherapy using dynamic MRI
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Biogen/Icos LFA-1 collaboration is concluded
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BioSante signs biodefense vaccine CRADA with U.S. Army
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Final phase IIa results from kidney transplant study of ISA-247
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ATL-1101 silences target gene in lab psoriasis studies
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CHF-3381 proceeds to proof-of-concept study
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Four related series of antiviral neuraminidase inhibitors reported by Biota
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New alpha4 integrin antagonists and their use in IBD, asthma, arthritis, etc.
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Novel glycogen phosphorylase inhibitors prepared and tested by JT researchers
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AstraZeneca scientists present new P2X7 receptor antagonists in a recent patent
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New cannabinoid CB2 receptor ligands in early development at Schering-Plough
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New PDE5 inhibitors in Schering-Plough development pipeline
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Compounds able to inhibit HDM2 or MDM2 binding to p53 and their use as antitumor agents
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Inverse agonism of the CB1 receptor increases energy expenditure
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Serotonin 5-HT6 receptor antagonism attenuates food intake and body weight
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HMR-1426: a potent orally active anoretic
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