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BioWorld - Monday, January 26, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

Oct. 27, 2003

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Vical enters CRADA for West Nile virus vaccine development

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Crucell malaria vaccine candidate to be evaluated in two collaborative programs

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Ranbaxy and GSK enter drug discovery and development collaboration

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Two series of alpha7 nAChR agonists prepared and tested at Bayer

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New synthetic pateamine A analogues and their use as immunosuppressant agents

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Novel HIV protease inhibitors developed by U. of Illinois researchers

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Ariad describes bone antiresorptive proteasome inhibitors and their use

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Quinoline-based PDE4 inhibitors and their use covered by Merck Frosst patent

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New mGluR5 antagonists identified by Merck researchers

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Merck claims new androgen receptor modulators for osteoporosis and other disorders

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Positive results reported for ABR-215757 in a murine model of systemic lupus erythematosus

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SB-431542, a potent inhibitor of TGF-beta signaling

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New COX-2 inhibitor from Almirall effective in animal models of arthritis

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BIRB-796, a p38 MAP kinase inhibitor, blocks both kinase activation and kinase activity

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The synthetic chalcone AGI-2048 shows promise as an oral DMARD for RA

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Met-RANTES, a CC chemokine receptor antagonist, shows activity in rat arthritis model

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Alpha-lipoic acid found to suppress joint inflammation and destruction in murine arthritis

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mTOR inhibitor RAD-001 in antibody-mediated autoimmunity

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Top-line results from third phase III study of Entereg for postoperative ileus

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Positive opinion handed down by CPMP for Advate

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CETi-1 produces increase in HDL cholesterol in phase II trial

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Dyax and URRMA enter alliance to develop anti-R7V antibodies for HIV

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Avandamet approved in E.U.

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Starlix approved in combination with TZD for type 2 diabetes

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Yondelis receives E.U. orphan drug status for ovarian cancer

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Roche and Nippon Shinyaku to develop drugs for dyslipidemia

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Remicade approved in E.U. for maintenance dosing in fistulizing Crohn's disease

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Preclinical studies support further development of MB-7133 for HCC

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