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BioWorld Science

Nov. 5, 2003

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Systemic inflammation increases cardiovascular risk in rheumatoid arthritis

Relationship between fracture risk reduction and improvement in BMD

Study of transplanted replacement islets without long-term immune suppression

metaGen to merge with Astex Technology

Cell patch cardiomyoplasty potentially useful in the surgical treatment of heart failure

Efficacy of omalizumab in concomitant asthma and rhinitis

Potential therapeutic role suggested for simvastatin in pulmonary hypertension

New 5-HT6 receptor ligands and their use reported by GSK researchers

Novel cytokine release inhibitors identified at Procter & Gamble

Merck presents new KSP inhibitors with utility in cancer therapy

Shionogi team synthesizes new antibacterial cephems

Merz claims new antagonists of NMDA, 5-HT3 and acetylcholine receptors and their use

New analgesic vanilloid VR1 antagonists identified at Merck

Two series of PAI-1 inhibitors designed by Schering AG researchers

Improved quality of life associated with cilomilast in COPD

Benefits described for pirfenidone in the treatment of NASH and liver cirrhosis

Preclinical and clinical development efforts at Actelion

Avigen presents phase I protocol for AV-201 to FDA advisory committee

Approval received for Sucanon in Mexico

Chiron grants license to Rigel for hepatitis C technology

IR-103 enters preclinical development program for HIV

Enrollment completed in phase IV pediatric study of Altace

Merck subsidiary seeks approval for Erbitux in Australia

Positive results reported from phase IIb study of PT-141

NDA submitted for pregabalin

Uroxatral launched in U.S.

Teva announces plans to acquire Sicor

DTI grant for Xcellsyz drug development efforts

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