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BioWorld - Friday, December 5, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 18, 2003

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Medtronic initiates Talent(TM) Thoracic Stent Graft Study in the US

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Caspase-3 inhibition preserves myocardial geometry and long-term function postinfarction in mice

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Neramexane shows promise for the treatment of alcohol dependence

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Antalarmin reduces volitional ethanol consumption in rats

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Hyperforin, an antidepressant with a novel mechanism of action

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Pharmacological profiles of novel dual D2/5-HT1A-acting antipsychotics

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Antidepressant/anxiolytic effects of CP-154526 shown in a rat model of depression

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Proton pump inhibitors and cytochrome P-450 polymorphism in GERD

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Therapeutic benefits of rabeprazole in ulcers and GERD

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BIA-2-024 and BIA-2-093 reported less neurotoxic than current antiepileptics

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Fast and potent analgesic effects of AZD-3582 in a rat model of monoarthritis

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First evidence of antiinflammatory effects induced by cilomilast in COPD patients

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New thyroid receptor antagonists and their use described in Karo Bio patent

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Solvay scientists describe novel NK1 antagonists for pain, emesis, arthritis, etc.

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Novartis claims MMP inhibitors with utility in neuropathic pain therapy

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Gruenenthal patent covers new NBTI analogues with potential as analgesic agents

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New NR2B NMDA antagonists in early development at Merck

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Novel factor Xa inhibitors prepared and tested at Merck KGaA

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New M3 antagonists/PDE4 inhibitors for COPD and other uses claimed by UCB team

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Pliva presents azulene-based inhibitors of TNF-alpha and/or IL-1 production

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Two phase III studies for Retaane planned for January

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BTG seeks development partners for PDE-4 inhibitor portfolio

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Encouraging results for Crucell's experimental malaria vaccine

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Dendreon grants Kirin HLA-DR antibody license, regains Asian Provenge rights

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Swiss prenotification of intent to approve Erbitux

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Nobex to reacquire modified insulin molecule rights from GlaxoSmithKline

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Arthron compounds produce sustained suppression of rheumatoid arthitis

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Sinovac new name for Net Force Systems

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Subcutaneous CERA increases plasma hemoglobin in patients with chronic renal anemia

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Good safety profile found for pyridoxamine in patients with diabetic nephropathy

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