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Home » Newsletters » BioWorld Science

BioWorld Science

March 29, 2004

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Lovastatin reduces expression of ER-alpha in human breast cancer cell lines

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Synergistic action of rosiglitazone and gemcitabine observed in pancreatic cancer cell lines

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Novel antinociceptive effects and pharmacokinetics reported for SCIO-469, a p38 MAPK inhibitor

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New antibacterial oxazolidinones prepared and tested at Pfizer

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New antitumor lamellarin analogues developed at PharmaMar

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Predix presents new NK1 antagonists for asthma, pain, emesis, etc.

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Novel DPP-IV inhibitors under study at Takeda

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Novel progesterone receptor modulators and their use in contraception and gynecological disorders

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New mGluR5 antagonists discovered by AstraZeneca and NPS team

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Positive results from phase III indiplon trials

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Follistim-AQ receives FDA approval

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Loss of allergen sensitization reported in children between two and four years of age

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New data on the use of epinephrine in the treatment of allergies

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Prevention of HBV reactivation during chemotherapy in breast cancer patients

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A HER-2 protein vaccine shows promise in breast cancer immunotherapy

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BMS-068645 enters phase II trials

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Orphan drug designation for pirfenidone for IPF

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Active Biotech TTS candidate drug shows promise in pancreatic cancer

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Pivotal study for PW-2102 meets primary endpoint

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Shire to develop extended release formulations of Q-8003

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Enrollment completed in phase IIIb Xyrem study

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Inspra approved in Netherlands

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Enhance Biotech selects Covance to test LI-313 compound in clinic

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Aventis submits new U.S. and E.U. regulatory submissions for Taxotere

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Enhanced efficacy of chemotherapy when used with OncoVEX in tumor models

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European CPMP recommends approval of Erbitux in colorectal cancer

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Merck to discontinue development of EMR-62203

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SGN-40 enters phase I trial for multiple myeloma

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German consortium to develop TB vaccine

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Novel retinoid-related ligand presented by Allergan at AACR meeting

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Antitumor activity of JNJ-7706621, an orally available CDK inhibitor, demonstrated in vivo

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Final results of the ACTION I study for pimagedine in diabetic nephropathy

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Patient exposure and response to pregabalin in GAD

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Novel PDE5 inhibitor for erectile dysfunction by Schering Plough

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