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BioWorld Science

April 23, 2004

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In vitro, in vivo and pharmacodynamic evaluations of Flt-3/KDR inhibitor

Telbivudine reported more effective than lamivudine in chronic hepatitis B

Different mechanisms suggested for HCV resistance to VX-950 and BILN-2061

Low incidence of anemia found with viramidine/pegylated interferon alfa-2a in HCV-infected patients

Therapeutic benefits of Alzhemed(TM) in patients with mild Alzheimer's disease

Evidence for cognitive improvement associated with phenserine in Alzheimer's disease

NCX-8001 reduces pain-like behavior in two rat models of neuropathic pain

Dual ACE/neural endopeptidase inhibitor AVE-7688 ameliorates diabetic nephropathy in obese ZDF rats

Glycopeptide antibiotics with antiviral activity prepared and tested at K.U. Leuven

Two series of HNE inhibitors prepared and tested by Bayer scientists

Novel Raf kinase inhibitors under study at Merck KGaA

New oxytocin inhibitors with potential in premature ejaculation treatment

New PPAR agonists for type 2 diabetes claimed by Merck

Kosan presents erythromycin-based motilin agonists

Adenosine deaminase inhibitors effective against inflammation and leukemia in vivo

Highly potent nociceptin/orphanin FQ peptide receptor agonist

Pariet approved in E.U. for on-demand GERD therapy

BioMarin to acquire Medicis' pediatric business

Proscar therapy approved to reduce risk of BPH symptom progression

Nycomed to develop and market Preos in Europe

Improved pharmacokinetics, antitumor activity and tolerability for liposomal vinorelbine

Elan licenses NanoCrystal technology to Roche

BTG licenses abiraterone acetate rights to Cougar

Inflazyme completes acquisition of Adprotech

New pilot trial studies Incert-S antiadhesion therapy

MedImmune and Cerus to codevelop novel therapeutic vaccine

Oxford BioMedica reviews Q1 progress

CG-53135 enters new phase I trial in bone marrow transplant patients

Advexin subject of new SWOG phase II trial

Dynport completes preclinical testing of recombinant plague vaccine

Gatiflo eye drops receive Japanese approval

Preclinical and clinical evidence for the benefits of IDN-6556 in liver disorders

Antiviral effects of NM-283 in chronic hepatitis C patients