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BioWorld Science

May 7, 2004

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Sustained improvement achieved with daclizumab in relapsing/remitting MS

Antibiotics and C. pneumoniae clearance in multiple sclerosis

Farnesyl pyrophosphate synthase inhibitor risedronate found effective against Trypanosoma cruzi

Antitransferrin receptor antibody induces apoptosis in acute T-cell lymphoma

Angiocol inhibits retinal angiogenesis in vitro

Synergistic effects of AM-251 and an opioid antagonist on food intake in mice

ABT-894 selected for development from NeuroSearch/Abbott collaboration

Johnson & Johnson highlights first quarter developments

Effective prevention of migraine achieved with coenzyme Q10

Therapeutic benefits of pioglitazone in several diabetic complications

Melatonin reduces blood pressure in patients with type 1 diabetes

Effective normalization of IGF-1 levels achieved with pegvisomant in acromegaly

Japanese team presents hemoglobin-derived plasmin modulators

New PARP inhibitors covered by Kyorin patent

Novel Rho kinase inhibitors prepared and tested at Kirin Brewery

Japanese researchers describe a potential H. pylori vaccine based on urease-derived peptide

Peripherally acting antitussive agents claimed by Tsumura scientists

Novel antihistaminic agents in early development at Sumitomo

Safety and pharmacokinetic profile of PL-100

Roche completes registration program for Pegasys in hepatitis B

Incara files IND to commence clinical studies of AEOL-10150 for ALS

PMA for GEM-21S accepted for review

CombinatoRx to test Immtech compounds for cancer

New phase II study begins for SDX-105 in NHL

Approval of rhBMP for orthopedic trauma patients

GTC signs agreement with Mayo Clinic for agonistic antibody to CD137

BTG acquires diabetes and neurodegeneration programs from King's College

NaPro BioTherapeutics becomes Tapestry Pharmaceuticals

Dosing commences in phase II metastatic colorectal cancer study for CoFactor

Arena highlights selected developments during first quarter of 2004

Novel somatostatin analogue may be effective in diabetic retinopathy

Dose-dependent activity of EGT-001 in ocular angiogenesis model

NO-releasing derivative of naproxen shows comparable efficacy with less gastric damage