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BioWorld Science

June 9, 2004

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Discovery milestone in ChemBridge/Eisai GPCR collaboration

KaloBios inlicenses antibody to treat and prevent Pseudomonas infections

Trimeris and Array BioPharma renew antiviral drug discovery agreement

Novel gabapentin prodrug with enhanced efficacy

Protective effect of antioxidant and free radical scavenger on chondrocyte viability after injury

TP-508 enhances cartilage repair in rabbits

Mechanism of fluid retention by PPAR agonist GI-2570X

Selective inhibitor of glycogen synthase kinase-3 stimulates glucose uptake in adipocytes

Sumitomo licenses licofelone for Japan

European approval for Abilify for schizophrenia

Tosufloxacin tosilate eye drops submitted for Japanese approval

Alteplase filed for approval in Japan

Merck KGaA to return Theratope rights to Biomira

Istalol NDA for glaucoma approved

Incara to revise phase I protocol for AEOL-10150

Levemir receives European approval

Antisoma updates recent development efforts

Investigations of olmesartan reported at ADA congress

Recombinant GAD65 shows promise in latent autoimmune diabetes in adults

Adenosine receptor antagonist improves insulin sensitivity

Intranasal insulin improves memory function

Two series of CGRP antagonists and their use in migraine and other disorders

GSK researchers prepare and test two series of histamine H3 antagonists or inverse agonists

Novel DPP-IV inhibitors in early development at BMS

Novel quinazolinone-based factor Xa inhibitors developed by BMS scientists

Metabolic disease crosstalk and the potential role of PPAR agonists

BTG claims dual AChE/5-HT reuptake inhibitors for AD, depression, etc.

ProSavin improves motor function and clinical rating scales in parkinsonian macaques

RNAi therapy for spinocerebellar ataxia type 1