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BioWorld Science

June 25, 2004

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Transgene highlights first quarter developments

Broad antitumor activity reported for Veglin in vivo

Orally active small molecule erythropoietic agent for the treatment of anemia

Panitumumab demonstrates encouraging antitumor activity

Bevacizumab demonstrates substantial clinical activity

Green tea extract may reverse tetracycline resistance

Metabolic conversion of anticancer agent SD-2007 to apicidin in rats

Topical tacrolimus found to improve skin lesions in patients with connective tissue disease

Remicade approved in E.U. for early rheumatoid arthritis

North American phase III trial initiated for Alzhemed

New European approval for Herceptin

Good safety profile reported for AP-23573 in patients with refractory tumors

Exanta launched in Germany

FDA lifts clinical hold on phase I NHL study of PPI-2458

GPI-0100 to be studied by Memorial Sloan-Kettering under new agreement

New trials to expand StaphVAX potential beyond ERSD patients

Liarozole receives U.S. orphan drug status for congenital ichthyosis

Immusol initiates collaboration with Affymetrix for oncology drug discovery

XenoPort presents new gemcitabine prodrugs

Novel HCV NS5B inhibitors jointly reported by ViroPharma and Wyeth

Roche claims two series of protein kinase inhibitors for use in cancer therapy

Three series of orexin antagonists patented by GSK researchers

New antibacterial agents covered by GSK patent

New antitumor agents developed by Sanofi-Synthelabo scientists

Mepolizumab reduces allergen-induced eosinophils and tenascin deposition

R-483 studied in animal models, diabetic patients

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