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BioWorld Science

Aug. 25, 2004

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Arsenic trioxide inhibits HCV replication in vitro

MGI Pharma updates recent developments

Novel antibactericidal agent against resistant gram-positive strains

Potent antiinflammatory activity identified for erythromycin derivative

Novel analgesic with fewer side effects for control of chronic pain

European Commission clears Yamanouchi/Fujisawa merger

Warner Chilcott updates development progress

New cytotoxic nitrogen mustard with potent antitumor activity

Apax Partners forms Aerovance

COX-2 inhibitor shows antitussive effects in guinea pigs

New CRF antagonists under study at Taisho

BioProgress to enter option agreement with Micap for smoking cessation products

New LXR modulators designed by researchers at X-Ceptor and Sankyo

Vertex presents novel caspase inhibitors with potential in CNS disorders

Vertex researchers claim two series of heterocyclic inhibitors of JAK3 and other kinases

FDA approves Zelnorm for chronic constipation

Schering-Plough exercises option to license pleconaril

Financing at Agile Therapeutics to fund transdermal contraceptive

Transition Therapeutics licenses Islet Neogenesis Therapy to Novo Nordisk

Four series of FAK, MEK and Trk inhibitors presented by Pfizer

CRF1 receptor antagonist SSR-125543A shows antidepressant and anxiolytic effects

Pharming acquires patent portfolio of PPL Therapeutics

Geodon approved for acute bipolar mania

BioMarin files IND for Phenoptin

Lilly launches Cymbalta

Newly identified MCH receptor antagonists reported to reduce food intake and body weight gain

Antimitotic agents from Abbott inhibit both angiogenesis and tumor growth

Orally active nonpeptide aquaretic V2 antagonist advanced to human testing

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