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BioWorld Science

Sep. 8, 2004

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Oral ibandronate found to reduce fracture risk in postmenopausal osteoporosis

Antitumor effects of an oblimersen/docetaxel combination in hormone-refractory prostate cancer

Novel PPARalpha/PPARgamma agonists discovered at Merck KGaA

New Na+/Ca2+ exchanger inhibitors and their use as antiarrhythmic agents

BMS patent covers new tyrosine kinase inhibitors for use in cancer therapy

5-HT/norepinephrine reuptake inhibitors and their use in depression, anxiety and pain

Novel TNF-alpha production inhibitors discovered by Italian scientists

Novel Bcr-Abl kinase inhibitors prepared and tested at Sloan-Kettering

Bioxel researchers claim new taxane-carbohydrate conjugates

Nautilus and Creabilis to develop improved variant of CT-500

DigiFab submitted for approval in U.K.

Tentative approval in Mexico for confirmatory phase III study of Theraherp

Enrollment underway in third phase I study of CYC-682

Valentis expands licensing agreement with Genzyme

Public registers to disclose clinical trial information

Gatiflo eye drops launched in Japan

Promising pharmacokinetic data found with inhaled ciclesonide in asthmatic patients

AVE-5883 reduces airways response to NKA in asthma patients

Therapeutic benefits of EPI-12323 in allergic asthma

Liraglutide increases the effects of metformin on glycemic control of diabetic patients

JTZ-132 induces megakaryopoiesis in CD34+ cells

Cymbalta approved for diabetic peripheral neuropathic pain

ITB may protect osteoarthritic cartilage from damage

Studies reveal preclinical activity and tolerability of SOM-230

R-483 reduces insulin, triglycerides in type 2 diabetes model

CDB-4124 superior to RU-486 in breast cancer model

ISF-402 mechanism of action explored in vivo

Activity of DPP-IV inhibitor GRC-8087 characterized in vitro, in vivo

DPP-IV inhibitors effective in model of impaired glucose tolerance

Pain Therapeutics reports Q2 progress

Curis highlights second quarter developments

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