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BioWorld Science

Oct. 15, 2004

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Statins may promote new bone formation via induction of PI3K signaling pathway

News in Context, a new feature of DailyDrugNews.com

Broccoli derivative shows cytotoxicity in bladder and prostate cancer cell lines / News in Context

Two series of glucokinase activators reported by OSI scientists

Novel PEPCK inhibitors prepared and tested at Roche

New xanthine-based adenosine A1 antagonists covered by Endacea patent

New analgesic agents identified by Italian researchers

Roche presents new anti-HIV reverse transcriptase inhibitors

Novel inhibitors of EGFR-mediated signal transduction claimed by Boehringer Ingelheim

New anti-HIV agents in early development at Janssen

Encysive presents new urotensin II/CCR9 antagonists and their use

Enrollment completed in adult insomnia phase II study of SO-101

alpha-TEA and vitamin E succinate active in preclinical cancer models

Launches and court orders for generic gabapentin

Approval for new Cancidas indication

DX-88 granted fast track designation for HAE

Proof-of-concept study of NPS-1776 in migraine fails to meet primary endpoint

Tripep completes preclinical safety studies for alpha-HGA

Expert analysis supports continued development of ENT-103

Extension study results for PBT-1 in Alzheimer's

Fast track designation for StaphVAX

Dynogen licenses compounds from Newron

Phase I study for PowderMed's novel therapeutic herpes simplex 2 DNA vaccine

Fast track designation for FK-228 for CTCL

Positive phase I findings for CTI-01

European orphan drug designation for TheraCLEC

Positive preliminary results for phase I study of oral PTH

New two-part phase I trial with ThGLP-1

Aviscumine shows antitumor effects and a good safety profile in refractory cancer patients

Oral CP-547632 shows promise in the treatment of advanced solid tumors

SB-715992 dose-dependently reduces ANC in patients with solid tumors

Long-term octreotide restores gonadal function in male patients with acromegaly

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