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BioWorld - Saturday, December 6, 2025
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BioWorld Science
Nov. 2, 2004
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Three novel series of vanilloid VR1 antagonists presented by GSK
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New melanocortin MC4 agonists under study at Merck
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Abbott researchers describe new dopamine D3 ligands for schizophrenia and depression
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Novel Chk1 inhibitors and their use covered by AstraZeneca patent
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New tubulin polymerization inhibitors prepared and tested at Aventis
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AstraZeneca scientists design novel gamma-secretase inhibitors
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Novel CDK2/CDK5 inhibitors claimed by IRM researchers
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Bile acid transport inhibitors may lower plasma cholesterol levels
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A3 adenosine receptor agonist inhibits the development of experimental arthritis in vivo
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Novel hypoxia-targeting agents for tumor therapy
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Orphan drug designation for BAY-43-9006 for renal cell carcinoma
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European launch for Angiox
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Further restructuring at Savient
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Aridol asthma test meets endpoints in phase III study
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Provenge extends survival of advanced prostate cancer patients in phase III study
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Tumor responses in phase I study of Proxinium for head and neck cancer
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Recent progress with Imvamune
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ARRIVE 2 registry program begins enrollment
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Enrollment completed in phase II Pneumocystis carinii study of DB-289
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Delay to roflumilast regulatory filing in U.S.
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Roche and Pharmasset to develop new generation HCV therapies
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Mimpara approved in Europe
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BAL-4079 enters phase III for severe chronic hand dermatitis
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Novel platelet-specific nitric acid donor inhibits experimental thrombogenesis
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Insulin enhances memory, mood in healthy subjects
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OPC-28326 reduces the frequency of secondary RP attacks in patients with scleroderma
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BPC-157 improves myofibrotic contracture in animal model
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Mechanism of action of DMARD T-614
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New data on the effects of the antisense inhibitor ISIS-301012
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Abatacept effective in RA patients inadequately responding to methotrexate or TNF-alpha inhibitors
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Laquinimod pharmacokinetics assessed in relapsing multiple sclerosis patients
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Interleukin-12 produces responses in non-Hodgkin's lymphoma patients
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