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BioWorld Science

June 23, 2005

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APD-125 promotes and consolidates sleep in rats

Cannabinoids reported to improve motor and vocal symptoms of Tourette syndrome

Targeting of enzymes involved in intermediary lipid metabolism with ASOs improves insulin resistance

In vitro and in vivo data on telomerase inhibitor GRN-163L published

GW-506U78 shows antitumor activity in relapsed/refractory T-ALL and T-LBL

Update on Spheramine in the treatment of Parkinson's disease

Positive topline phase III results for iduronate-2-sulfatase in Hunter's syndrome

ImClone to file sBLA for Erbitux in head and neck cancer in Q3

New phase I study evaluates VX-680 in hematologic cancers

Enrollment completed for phase III study of Vitor in cancer cachexia

FDA extends action date for Aceon sNDA review

Intranasal Technology and Aegis expand collaboration

GSK Biologicals and IAVI to develop AIDS vaccine

DARPA sponsors shift work study of CX-717

AnGes licenses NFkB decoy oligo for degenerative intervertebral discs

BAY-65-6207: a glucose-dependent insulin secretagogue in vitro and in vivo

New small-molecule Hsp90 inhibitor from Vernalis shows clinical candidate potential

T-817MA prevents and reverses decline in cognitive function in rats and mice

Promising preclinical results with insulin analogues in basal glycemic control

Priority review for Exjade

BioMarin launches Naglazyme for MPS VI

Revlimid receives priority review

Tamsulosin OCAS begins roll-out in Europe

HSV-TK-positive donor lymphocytes prevent development of GvHD in stem cell transplantation

Approvable status for Implanon implantable contraceptive

Accelerated approval for Aptivus in HIV

Epratuzumab shows promise in the treatment of primary Sjogren syndrome

Promising in vitro and in vivo results for glycogen phosphorylase inhibitor Gpi-688

Rimonabant NDA accepted for filing

Recent patents describe therapeutic agents for respiratory and inflammatory disorders