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BioWorld Science

Dec. 14, 2005

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Gene Logic and Roche sign drug repositioning and development agreement

MedImmune licenses Eph-targeting peptides from Burnham Institute

New phase II trial investigates satraplatin plus Taxol for advanced NSCLC

BPI: A BCL6 peptide inhibitor that reactivates p53 tumor suppressor

Lilly reviews pipeline progression

Valomaciclovir rights revert to Medivir

LU-AA24530 enters the clinic

Pain Therapeutics discontinues further development of PTI-901

Further clinical assessment of lacosamide

Xopenex HFA now available

Orphan drug designation for Cethrin

New phase IIa study of oral RSD-1235 to prevent recurrence of atrial fibrillation

Phase II study of Epadel for Alzheimer's dementia finishes early

Compounds with potential in the treatment of HIV infection disclosed

Recent patents of agents for cardiovascular disorders

Ambrisentan PAH study shows significant improvement in six-minute walk distance

New candidates for sickle cell disease

The antiepileptic seletracetam inhibits HVA Ca2+ currents and intracellular Ca2+ elevations

Zanolimumab active, well tolerated in CD4+ peripheral T-cell lymphoma

Evidence of activity seen with KOS-953-trastuzumab in metastatic breast cancer patients

GW and Almirall announce European development and marketing agreement for Sativex

Increlex MAA filed in Europe

Data on SB-715992 in advanced or metastatic breast cancer reported

E-7389 monotherapy demonstrates potential in refractory breast cancer

KOS-862 active in anthracycline- and taxane-resistant breast cancer

Tocosol Paclitaxel evaluated as first-line treatment of metastatic breast cancer

Glivec submitted in Europe for adult patients with Ph+ ALL

NDA submission for arformoterol for COPD

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