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BioWorld Science

Jan. 27, 2006

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2005 achievements at VioQuest

MKC-733 demonstrates potential in constipation

Inhaled hypertonic saline benefits cystic fibrosis patients

p53 tumor suppressor harbors antioxidant function

NEPP compounds provide neuroprotection via modulation of Keap1/Nrf2 to activate HO-1

New GPR109b agonists as antilipolytic agents

Novel nonsteroidal selective 5alpha-reductase type 2 inhibitor presented

Novartis makes steady progress in Q4

Metaglidasen as effective as thiazolidinediones for glycemic control

Xience V stent system moves closer to European approval

Orphan drug designation for ACR-16 for Huntington's disease

Guidant settles on merger with Boston Scientific

Kosan studies oral Hsp90 inhibitor KOS-1022 in phase I trial

Transgene receives funding for HCV therapeutic vaccine program

Manufacturing milestone in RiVax development

Updated labeling approved for Elidel and Protopic

Orphan drug status for Myodur in Duchenne and Becker muscular dystrophies

Targeted Genetics restructures

Phase I study for EM-1421 in unresponsive tumors

Dainippon Sumitomo and Aska end agreement

NeuroSearch to continue development of tesofensine

European approval for Kiovig

New IP receptor antagonists from Roche show analgesic potential

Recent AstraZeneca patent reports novel GABA-B receptor modulators

Recent patents report novel agents for obesity and lipoprotein disorders

Novel tachykinin NK1 antagonists disclosed in recent Merck & Co. patent

Ono patents novel compounds for transplant rejection

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