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BioWorld Science

April 18, 2008

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Antiviral effects of rapamycin in mouse model of HIV infection

SRI-21950 active against vaccinia and cowpox viruses in mice

Lexicon presents early clinical results of LX-6171 at the AAN meeting

Proposed merger between Inflazyme and Z-Tech is terminated

Fusion construct targeting carcinoembryonic antigen cytotoxic in vitro

XIAP knockdown allows cancer cell apoptosis with TRAIL in resistant cells

New farnesoid X receptor agonist shows preclinical potential in dyslipidemia

FDA accepts Huya's IND-enabling nonclinical and clinical development plans for chidamide

E.U. approves new powerful antihypertensive MicardisPlus 80/25

Kythera commences second phase II ATX-101 trial for reduction of submental fat

Pfizer completes tender offer for shares of Encysive

Phase II trial shows safety and immunogenicity for Japanese encephalitis vaccine

SIGA advances ST-246 smallpox candidate development in Europe

Avapro obtains Japanese manufacturing and marketing approval

FDA grants fast track designation for RG-1068 in pancreatic imaging

FDA grants orphan drug designation for Zymenex's enzyme, Metazym

Insert initiates phase II clinical trial with lead drug candidate IT-101 for ovarian cancer

Novel antipsychotic YKP-1358 shows good safety and D2 receptor affinity in humans

MethylGene initiates phase I clinical trial for MGCD-265 in solid tumors

Novartis receives approval for Exjade in Japan

Ono and Dainippon Sumitomo discontinue limaprost in cervical spondylosis

Aldagen initiates treatment in phase III clinical trial of ALD-101 for cord blood transplants

New antiinflammatory agents reported in recent Nycomed patent

Novartis divulges novel S1P1 receptor agonists in recent patent

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