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BioWorld Science

April 6, 2010

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Aldosterone synthase inhibitor LCI-699 shows promise in hypertension trial

Reduced risk for stroke and embolism with dabigatran compared to warfarin in RE-LY trial

Unfavorable risk-benefit noted with anticoagulant/antiplatelet therapy in atrial fibrillation

NeuroSearch claims nicotinic acetylcholine alpha7 receptor ligands and monoamine receptor modulators

Probiodrug discloses novel glutaminyl cyclase inhibitors

New SCD-1 inhibitors discovered by sanofi-aventis

Biolipox presents new leukotriene C4 synthase inhibitors

Auckland Uniservices discovers novel nitrobenzindole prodrugs for treatment of cancer

Merck & Co. selects antiobesity CB1 inverse agonist MK-5596 as clinical candidate

Regadenoson in myocardial perfusion imaging exhibits safety in heart transplant patients

Pfizer discloses identification of selective PDE9 inhibitors at ACS meeting

FDA allows GeoVax to start phase I clinical trial of HIV vaccine

NeurOp and Bristol-Myers Squibb enter drug discovery collaboration

Stem Cell Therapeutics completes enrollment in phase IIb REGENESIS stroke trial

QRxPharma begins phase I trial of CR morphine/oxycodone for chronic pain

ViroPharma begins phase II Cinryze trial in pediatric HAE patients

VIA Pharmaceuticals reports strategic restructuring and R&D pipeline update

GSK's Duodart approved for benign prostatic hyperplasia in E.U.

Ardea reports phase IIb RDEA-594 monotherapy data in hyperuricemia and gout

Orexigen submits NDA in U.S. for Contrave obesity treatment

GSK and Isis to develop RNA-targeted therapeutics for rare and infectious diseases

AMAG and Takeda enter into agreement to develop and market Feraheme

ArQule reports phase II data on ARQ-197 in non-small cell lung cancer

Phase II data reported for OMS-103-HP in arthroscopic meniscectomy surgery

Symphogen begins phase I/II Sym-004 trial in advanced solid tumors

Alzheimer's Drug Discovery Foundation funds Signum Biosciences' research

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