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BioWorld Science

Oct. 21, 2010

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New antibiotics for multidrug-resistant pathogens in preclinical/clinical evaluation

Zealand Pharma's ZP-2307 shows bone anabolic activity in vivo

Subanalyses of CLARITY data support benefits of cladribine tablets

EC grants orphan drug status for eflornithine in familial adenomatous polyposis

Sequella and LMU to collaborate on phase II SQ-109 trials

Treatment begins in phase I/II alpha-1-antitrypsin trial in type 1 diabetes

ONO-4641 shows safety and tolerability in phase I trial in MS

Phase I trial evaluates MVA-BN PRO in castration-resistant prostate cancer

New nicotinic acetylcholine alpha4beta2 receptor modulators claimed by NeuroSearch

New diacylglycerol O-acyltransferase 1 inhibitors disclosed

Plexxikon presents new inhibitors of protein kinases

Merck & Co. describes novel P2X3 receptor antagonists

Phase II trial begins of CAL-101/rituximab combination in CLL

ADL-5945 enters proof-of-concept phase II trial in opioid-induced constipation

Karmanos Institute receives grant to fund testing of HER2Bi-armed activated T cells

BEMA Fentanyl citrate approved in Europe for breakthrough cancer pain

FDA approves Pradaxa for reducing risk of stroke in patients with nonvalvular AF

Roche files to extend indication of tocilizumab for systemic juvenile idiopathic arthritis

ImmuneWorks begins phase I trial of its lead compound for IPF

Alexza Pharma reacquires U.S. and Canadian rights for AZ-004

Daiichi Sankyo launches Inavir in Japan

FDA issues complete response letter regarding Byuderon NDA

MKC-1106-MT enters phase II trial in advanced melanoma

EC grants orphan drug status for nafamostat mesilate in cystic fibrosis

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