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BioWorld Science

April 6, 2011

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MK-2206 advances to phase II testing in breast cancer

Phase II YF-476 trial begins recruitment of patients with Zollinger-Ellison syndrome

New PTEN/TP53/RB1 triple knockout model described of high-grade astrocytoma

Liver-selective glucokinase activator PFE-GKA-2 shows improved hypoglycemic control in vivo

RRx-001 to enter clinic as chemotherapeutic/radiosensitizer for cancer

Navitoclax enhances efficacy of taxanes in models of NSCLC

Vaccine based on rare adenoviral vectors is immunogenic in patients with HCV infection

Stealth Peptides presents phase I data on Bendavia

Probiodrug presents new glutaminyl cyclase inhibitors

Artemisinin is beneficial in patients with schizophrenia with elevated antibodies against T. gondii

Novel diacylglycerol O-acyltransferase 1 inhibitors reported

New androgen receptor ligands described by Bayer Schering Pharma

New compounds for treatment of HCV infection designed

FDA approves once-daily Viramune XR for use in combination for HIV-1 infection

United Paragon Associates patents new tachykinin NK2 receptor antagonists

OncoSec Medical and Inovio enter agreement for electroporation technology for cancer

Phase II PX-866 trial in glioblastoma begins enrollment

Quantum Genomics reports promising preclinical data on QGC-001

Merck & Co. acquires Inspire Pharma and expands ophthalmic pipeline

MedImmune enters strategic collaboration with Inserm Transfert

Progen Pharma completes enrollment in phase I trial of PG-11047

Favorable phase IIa data on NBI-98854 in patients with schizophrenia and tardive dyskinesia

Aragen Bioscience receives NIAID subcontracts to develop mAbs for infectious diseases

DARA BioSciences commences phase Ib study of DB-959

Enrollment completed in phase III trial of BEMA Buprenorphine for chronic pain

Celgene and ProMetic Life Sciences enter agreement for protein technologies

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