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BioWorld Science

May 20, 2011

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Abiraterone acetate plus prednisone provides clinical benefit in metastatic CRPC

New RAC-alpha serine/threonine-protein kinase inhibitors claimed

Novel PI3K-gamma inhibitors synthesized at Taisho

Stem cell therapy shows promise to treat diabetic retinopathy and optical neuropathy

Critical Outcome Technologies begins development of oral COTI-2 formulation

Armodafinil improves severe sleepiness in subjects with shift work disorder

Chemical genetics screening platform identifies new agent and target for influenza therapy

New liver X receptor agonists described by Merck & Co.

New tyrosine-protein kinase JAK3 inhibitors patented by Palau Pharma

Isis begins phase I trial of ISIS-TTRRx for transthyretin amyloidosis

Zydus-Cadila presents new peptidomimetic GLP-1 agonists/glucagon receptor antagonists

BAY-94-8862 enters phase II trial in patients with chronic heart failure and kidney disease

Medistem completes preclinical animal safety studies requested by FDA

Allergan patents novel alpha2C-adrenoceptor agonists

Resolve Therapeutics raises funds in series A financing round, plans next step for RSLV-125

Northwest Biotherapeutics and Fraunhofer enter partnership for DCVax-L

Ludwig Institute for Cancer Research and Polaris Pharmaceuticals form collaboration

FDA places new restrictions on use of rosiglitazone-containing medicines

TheraVida begins phase II trial of THVD-201

Japanese authorities approve additional indications for Novastan and Slonnon

Daiichi Sankyo's Rifadin approved for additional indication in Japan

Cell Therapeutics to meet with FDA next month regarding resubmission of pixantrone NDA

Eisai receives Japanese approval for additional indication of Vasolan formulations

Enzon Pharmaceuticals discontinues PEG-SN38 program in colorectal carcinoma

Omeros begins phase III program for OMS-103HP and OMS-302

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