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BioWorld Science

March 17, 2015

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SD-208 identified as protein kinase D inhibitor with oncolytic potential

Dacomitinib assigned U.S. orphan drug status for NSCLC

MitoNEET ligand TT-01001 has beneficial effects in diabetes model

Anti-AMHR2 antibody increases the efficacy of conventional first-line chemotherapy

Altor Bioscience begins phase I/II study of ALT-803 indolent B-cell non-Hodgkin's lymphoma

ACH-3422 shows low potential for mitochondrial toxicity

MacroGenics begins phase I study of MGD-010 for autoimmune disorders

ViiV Healthcare receives approval of Triumeq

ImMucin receives E.U. orphan drug designation for multiple myeloma

Exportin-1 inhibitors display beneficial properties in multiple sclerosis model

Valeant and Salix amend merger agreement, Endo withdraws offer

New York State approves Enzo Clinical Labs' FlowScript assay to detect HPV oncogene expression

Mezzion plans phase III studies of udenafil for adolescents with a single functional ventricle

Alsonex compound gains orphan drug status in U.S. for amyotrophic lateral sclerosis

Boehringer Ingelheim patents SMAC mimetics

Johnson & Johnson and GSK invest in Dementia Discovery Fund

Bristol-Myers Squibb describes indoleamine 2,3-dioxygenase inhibitors

PTC Therapeutics discloses new Bim-1 inhibitors

Sichuan Haisco Pharmaceuticals patents SGLT2 inhibitors

Minophagen applies for approval of bexarotene for CTCL in Japan

Endo launches nasal gel testosterone replacement therapy in the U.S.

Jakavi approved in E.U. for polycythemia vera

BioInvent and ThromboGenics plan phase I/IIa studies of TB-403 in medulloblastoma

ADC Therapeutics files IND for phase I trial of ADCT-301

Kyushu University and Tokyo Medical University patent MFG-E8 compositions

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