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BioWorld - Thursday, December 25, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

Oct. 1, 2015

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PROTACs: tagging disease-associated proteins for degradation

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C9orf72 knockout insufficient to cause motor neuron diseases in mice

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PeptiDream and Teijin agree discovery collaboration

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Bone Therapeutics initiates trial of ALLOB for minimally invasive revision spinal surgery

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Intrexon and Ziopharm Oncology form exclusive channel collaboration in GvHD

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PPOX identified as a new target for colorectal cancer therapy

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Aldeyra Therapeutics enrolls first patient in phase IIa trial of NS-2

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Novan Therapeutics reports IIb trial data for SB-204 for in acne vulgaris

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Macrophage Therapeutics produces first two immunoconstructs

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BLU-554 receives FDA orphan drug designation for hepatocellular carcinoma

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Polyphor/Roche macrocyclic peptide to combat multidrug-resistant bacterial infections

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PTC Therapeutics submits variation for new indication in Europe for Translarna

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BiondVax begins phase IIb trial of universal flu vaccine in Europe

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SEQ-9, a novel macrolide for the treatment of tuberculosis

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Zosano discontinues daily ZP-PTH and resumes development of weekly formulation

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Novel 2-pyridone antibacterials to treat Gram-negative bacterial infections

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AMO Pharma raises funds to advance clinical-stage candidates and expand pipeline

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reMYND develops new compounds for protein-misfolding disorders

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iTeos Therapeutics describes TDO2 inhibitors

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Tyme submits phase II IND application for SM-88

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Incretin effect identified as a predictor of prediabetes in women with previous GDM

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Trillium advances TTI-621 towards phase I trials

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Merck & Co. presents SYK inhibitors

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FDA awards QIDP designation to Ixogel for prevention of Lyme disease

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Ignyta initiates phase II trial of entrectinib

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BioMarin to acquire global rights to Kuvan and pegvaliase from Merck Serono

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