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BioWorld - Thursday, March 26, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

April 28, 2017

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Novartis reports key developments of first quarter 2017

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New phase III trial explores use of simvastatin in children with Noonan syndrome

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Xenon acquires potassium channel modulator for the treatment of epilepsy

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Sage Therapeutics begins phase I development of SAGE-718

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FDA grants breakthrough therapy designation to lorlatinib for ALK-positive metastatic NSCLC

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Aldeyra initiates phase III study of ADX-102 for noninfectious anterior uveitis

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ProQR Therapeutics cleared to begin phase I/II study of QR-110 in LCA 10

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RCM-1 reduces lung inflammation in response to HDM and recombinant IL-13 in vivo

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Promising interim phase I results for autologous EBV-specific T-cell therapy for MS

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Amgen profiles pipeline progress of first quarter 2017

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FOCUS results show promise of dimethyl fumarate in pediatric relapsing-remitting MS

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Preclinical efficacy of novel HBV expression inhibitor RG-7834 in combination therapy

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FDA approves Brineura to treat CLN2 disease

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New mouse model of acute alcoholic hepatitis developed

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Cellectar reports preclinical data on CLR-131 and CLR-125

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FDA approves Stivarga for second-line treatment of hepatocellular carcinoma

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Wnt signaling inhibitors patented by Suzhou Yunxuan Yiyao Keji Youxian Gongsi

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Inventiva discovers novel YAP/TEAD interaction inhibitors

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Pfizer seeks Japanese approval for inotuzumab ozogamicin in ALL

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Polyphor synthesizes new Pin1 inhibitors

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Universite Pierre et Marie Curie and collaborators identify novel RIP-1 inhibitors

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BridgeBio launches Eidos Therapeutics to develop AG-10 for TTR amyloidosis

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Sichuan Haisco describes novel muscarinic M3 antagonists and/or beta2-adrenergic receptor agonists

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Shanghai Hengrui and Jiangsu Hengrui Medicine discover mu-opioid receptor agonists

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Tavalisse accepted as proprietary name for fostamatinib disodium in U.S.

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Myriad Genetics and Clovis Oncology enter companion diagnostic collaboration for Rubraca

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Antibe Therapeutics begins IND-enabling preclinical studies for analgesic ATB-352

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New TLR5 polymorphism found to be associated with HCC in chronic hepatitis B patients

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Savara closes merger with Mast Therapeutics

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Agios and Aurigene in license agreement on small-molecule inhibitors of cancer metabolism target

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