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BioWorld Science

June 19, 2018

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Brain sleepiness signature, links to memory identified

FDA issues complete response letter for Duobrii lotion

Amgen initiates phase I trial of AMG-119 in small cell lung cancer

Safety run-in results presented from phase III ANDROMEDA study on daratumumab

Phase II results for talimogene laherparepvec plus pembrolizumab in patients with sarcoma

Forge Therapeutics LpxC inhibitor shows activity in vitro, in vivo and in combination

FDA grants fast track designation to mirvetuximab soravtansine in platinum-resistant ovarian cancer

Catalyst offers update from Cohort 6 in phase I/II trial of CB-2679d for hemophilia B

Agios initiates phase III ACTIVATE study of AG-348 in pyruvate kinase deficiency

Rhythm announces new topline clinical data for setmelanotide in rare genetic disorders of obesity

MXRA8, a drug-targetable receptor for chikunguya and other arthritogenic alphaviruses

Cognition Therapeutics initiates SPARC trial of Elayta in Alzheimer's disease

Clover initiates phase I trial of SCB-313 for malignant ascites

Sanofi completes acquisition of Ablynx

Roche and Foundation Medicine enter definitive merger agreement

FDA removes clinical hold on IGNITE DMD study of SGT-001

XMT-1522 demonstrates safety and preliminary efficacy in phase I study

Wellcome Trust grant supports Karuna's development of KarXT for schizophrenia

Xavier University of Louisiana divulges androgen receptor signaling inhibitors

Hedgehog pathway modulators patented by Development Center for Biotechnology, DCB-USA

Shanghai Institute of Materia Medica discovers BTK inhibitors

Glycogen synthase kinase 3 inhibitors patented by Bristol-Myers Squibb

FDA places clinical hold on phase I trial evaluating Ziopharm's CD19-targeted CAR T therapy

Alexion submits U.S. BLA for ALXN-1210 to treat PNH

First-in-human results reported for MK-1248 in advanced solid tumors

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