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BioWorld Science

July 18, 2018

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CRISPR reprograms T cells

Good-enough HCV vaccine could reduce transmission

BAFF and Beffs

Hot flashes are hypothalamic

Hearing light, no synesthesia required

ONO-8590580, a GABA(A)-alpha5 negative allosteric modulator enhancing hippocampal memory function

Novel CD-1db/db mouse model of type 2 diabetes with progressive kidney fibrosis

Discovery of novel PET tracer for imaging CSF-1R in the brain

First cohort dosed in phase I study of OMS-527

Blade Therapeutics initiates phase I study of BLD-2660

Cellectar reports 94% reduction in tumor volume in patient

Regeneron initiates phase I study of REGN-4659 plus cemiplimab in patients with NSCLC

Enrollment ongoing in phase II study of F-901318

Reactivated X chromosome produces functional Rett protein in mouse brains

Chinese researchers present preclinical data for DB-213, an HIV-1 replication inhibitor

Capricor Therapeutics' CAP-2003 to be studied for potential for trauma-related injuries

Voyager's VY-AADC program in Parkinson's guided by FDA and new phase I posterior trajectory data

FDA approves Symtuza for HIV-1 infection

Phase Ib results support Poxel's plans for phase II with PXL-770 in NASH

Roche and C4 Therapeutics patent EGFR mutant inhibitors

Pulmatrix reports data from Part 3 of first-in-human study of Pulmazole

Ono Pharmaceutical synthesizes PTK6 inhibitors

Italian researchers identify compounds for kinetoplastid infections

Oligomerix presents tau aggregation inhibitors

Merck & Co. divulges FFA1 receptor agonists