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BioWorld Science

Nov. 2, 2018

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Researchers develop new Drosophila model of PIGA deficiency

Chromatin map helps navigate cancer's landscape

Piezo2 mediates inflammation and nerve injury-induced sensitized mechanical pain in mice

Transplant-associated factors contribute to the long-term reduction in HIV reservoir after allo-HSCT

Novel association of CNTNAP2 with glaucoma progression identified

AEB-4104 prevents death and reverses liver pathology in mouse model of homocystinuria

MyoKardia provides pipeline update

AbbVie presents preliminary phase I data for ABBV-368

Greater clinical benefit observed in breast cancers treated with pegilodecakin and SOC chemotherapy

Biogen describes new Bruton tyrosine kinase inhibitors

Roche patents antibacterial macrocyclic oligopeptides

ILDONG Pharmaceutical discovers farnesoid X receptor agonists

Positive interim data presented from phase IIb study of MDNA-55 in recurrent glioblastoma

Daiichi Sankyo discontinues development of intradermal seasonal influenza vaccine

PAR and Parkinson's

Topline results reported from CLARITY phase II study of pimavanserin for MDD

Targeting IL1R signaling may abrogate obesity-induced colon cancer

ViiV Healthcare presents positive results from the phase III BRIGHTE study of fostemsavir

GlaxoSmithKline presents first-in-human data for GSK-3359609

European Commission approves Venclyxto with rituximab for relapsed/refractory CLL

BioSpecifics reports topline phase I data for CCH in uterine fibroids

Bavarian Nordic begins phase II dosing with BN-Brachyury in chordoma

Adverum discontinues development of ADVM-043, advances ADVM-022

Y-mAbs opens phase II/III study of [131I]omburtamab for neuroblastoma CNS/leptomeningeal metastases

New phase I/II study evaluates MK-4280 with pembrolizumab in hematologic malignancies

Galapagos initiates phase II PINTA trial of GLPG-1205 in IPF

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