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BioWorld - Wednesday, April 24, 2024
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BioWorld Science
Nov. 6, 2018
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IL-6-induced CD44 and PD-L1 expression confers cancer stem cell properties on bladder cancer cells
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JAVELIN: Strong data will drive practice in first-line renal cell carcinoma
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GPR40 activation alleviates epileptic seizures in animal models
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T-type calcium channel antagonists protect dopaminergic neurons from apoptosis in Parkinson's
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P2X7 receptor contributes to the hyperinflammatory response of localized aggressive periodontitis
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Phase I data presented for BVAC-C in HPV16- or HPV18-positive recurrent cervical carcinoma
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Preliminary results presented from TRITON2 study of rucaparib
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New fully human skin cell culture facilitates grafting
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TDP-43 aggregates at first do no harm
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Lenvatinib demonstrates highest overall response rate with a targeted agent in neuroendocrine tumors
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AK-111 begins first-in-human study in healthy subjects
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Denali and Sanofi collaborate to develop RIPK1 inhibitors
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ConSOSL.UFO replicon saRNA demonstrates high immunogenicity in vivo
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REWIND study of Trulicity meets primary efficacy objective
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Phase II study of GKT-831 in PBC meets primary and secondary interim efficacy endpoints
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Promising interim results presented from phase I DRIIV-1 study of AsiDNA
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PK and PD analysis in rhesus macaques of intravaginal ring containing the antiretroviral MK-2048
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Administration of TDP-43 inhibitor PM-1 stops progression of AD in 5XFAD mice
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Goldfinch Bio compound targets TRPC5 for the treatment of focal segmental glomerulosclerosis
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VX-659/tezacaftor/ivacaftor triple combination regimen shows safety and efficacy in phase II study
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Magenta Therapeutics patents AhR antagonists
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DKFZ and TUM present EPHA2 inhibitors
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International Stem Cell reports interim data from phase I study of ISC-hpNSC in Parkinson's
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Clearside Biomedical discontinues Xipere combination therapy for RVO based on SAPPHIRE data
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Eli Lilly identifies new EIF2AK3 inhibitors
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Eli Lilly and NextCure enter immuno-oncology discovery and development collaboration
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Bio-Thera Solutions initiates phase III trial of BAT-8001 in HER2-positive metastatic breast cancer
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Novintum Biotechnology divulges azithromycin derivatives for cancer
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Guangzhou Wellhealth Bio-Pharmaceutical discloses PARP-1 inhibitors
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Phase III TIVO-3 trial of tivozanib in renal cell carcinoma meets primary endpoint
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