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BioWorld Science

Nov. 26, 2018

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Mitochondrial pathophysiology linked to myocardial senescence

Targeting metabolism, not hormones, in prostate cancer

How MRSA makes itself look sweet

MATCH, a first-in-human, phase I, dose-escalation trial in cirrhosis

Phase II results presented for mocetinostat plus durvalumab in patients with NSCLC

Results from phase I/II study of INT230-6 in solid tumors

Arcus Biosciences patents adenosine A2A/A2B receptor antagonists

TAS-1553 demonstrates efficacy in preclinical models of hematological and solid tumors

First-in-human data presented for FAZ-053 monotherapy or in combination with spartalizumab

AB-122 demonstrates preliminary safety and activity in solid tumors

Improved mouse model of type A hepatic encephalopathy devised

European Commission approves pegfilgrastim biosimilar Pelmeg

MicuRx initiates phase II study of contezolid acefosamil in ABSSSI

Phase III study of VR-475 in severe uncontrolled asthma does not meet primary endpoint

Deleterious telomerase mutations identified in patients with end-stage liver disease

Juluca approved in Japan

Poxel begins part 2 of phase Ia study of PXL-065 for NASH

Pulmonary arterial hypertension model allows study of early intervention

PIONEER 6 trial of oral semaglutide demonstrates favorable CV safety profile

FDA places clinical hold on IND for first U.S. trial of ZGN-1061

RNAi therapeutic VIR-2218 begins phase I/II study for chronic HBV infection

Theravance initiates phase I study of TD-8236 by inhalation for asthma

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