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BioWorld Science

Dec. 19, 2018

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Administration of erlotinib via soaked intraocular lenses prevents posterior capsule opacification

Actuate begins phase I/II trial of GSK-3beta inhibitor 9-ING-41 in advanced cancers

CDK7 inhibitor THZ-1 induces breast cancer-specific cell death by suppressing LIN9 expression

Targeting NKILA in CTLs as a promising new breast cancer immunotherapy strategy

Irisin and bone: good but complicated

Premature birth complication prevented by targeting microglia

FAAH inhibitor PF-04457845 ameliorates stress- and fear-related behavior in humans

HP-3070 is efficacious and safe for the treatment of schizophrenia in adults

Selatogrel significantly inhibits platelet aggregation in phase II studies

Pyramid Biosciences licenses TRK modulator from AstraZeneca

TK-90 shows promise for prevention of mucositis in clinical study

Corbus initiates phase III DETERMINE study based on phase II data in dermatomyositis

Positive phase II data presented in third proof-of-concept study of VX-150

First patient enrolled in pivotal phase III AGENT study of arfolitixorin

Topline data presented from phase Ia study of LX-9211

Spiral Therapeutics initiates phase I trial of new hearing loss drug, LPT-99

Eli Lilly patents OGA inhibitors

Myelin needs just the right amount of neighborliness

Enanta Pharmaceuticals divulges MAP3K5 inhibitors

DuoHexaBody-CD37 induces potent CDC in ex vivo B-cell lymphoma and leukemia patient samples

Abide Therapeutics identifies MGL inhibitors

CD45-AM ADC as promising new approach for safer conditioning prior to bone marrow transplant

Oxford University Innovation discovers beta-lactamase inhibitors as antibacterials

Taisho Pharmaceutical describes bacterial LpxC inhibitors

Phase III study of satralizumab in neuromyelitis optica spectrum disorder meets primary endpoint

Repigmentation therapy with Scenesse and NB-UVB effective in vitiligo

DMC recommends stopping phase III study of lumateperone for futility

Lilly signs collaboration and license agreement for Aduro's cGAS-STING pathway inhibitor program

PeptiDream and Nihon Medi-Physics enter peptide-radioisotope conjugate alliance

European Commission approves Dengvaxia for prevention of dengue

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