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BioWorld Science

Feb. 18, 2019

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Downstream drugging improves RAS inhibition

Immune cell interaction key to better dengue vaccines

FDA accepts IND application for MT-8633

New zebrafish model allows screening for treatments for acute hyperuricemia

AGS signs research agreement with NIAID for experimental HIV/AIDS cell and gene therapy

PNP Therapeutics initiates phase I/II study of Ad/PNP-F-araAMP in local head and neck cancer

Bridge Biotherapeutics recruiting participants in first-in-human study of BBT-877

Huntingtin implicated in fragile X syndrome

Massachusetts Institute of Technology patents new AR antagonists

Lundbeck presents compounds for schizophrenia

Patient enrollment is ongoing in Akros Pharma's phase II study of JTE-451

Crinetics Pharmaceuticals discloses new somatostatin SST2 receptor agonists

Italian researchers synthesize new molecules targeting KCNH2 and ITGB1

Dual complement inhibition by CRIg/FH shows renoprotective effect in ischemia reperfusion injury

Codiak Biosciences describes new nanovesicles for inflammation-related conditions

NAPE-PLD, key regulator of intestinal fat absorption, liver lipid deposition and energy homeostasis

Innovent and Chipscreen collaborate to study chidamide, sintilimab and IBI-305 in colorectal cancer

Grant to support phase II development of AKL's APPA for osteoarthritis

First patient-derived xenograft models of primary central nervous system lymphomas

Docking library to include over 1 billion lead-like compounds for drug discovery

Biofabri initiates phase IIa study of TB vaccine candidate MTBVAC in South African neonates

Bionomics reports pharmacometric analysis of phase II RESTORE trial of BNC-210 for PTSD

Amgen begins first-in-human study of BiTE antibody AMG-160 in metastatic CRPC

New loci identified for type 2 diabetes in Japanese individuals

GlaxoSmithKline describes discovery of sulforaphane analogues for COPD