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BioWorld Science

Feb. 8, 2019

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A11 Mb-IRDye800CW is a promising new probe for real-time fluorescence imaging in prostate cancer

Alios BioPharma presents first-in-human data for AL-794

FEN1 and APEX2 as potential new targets in BRCA2-mutant tumors

FDA clears IND application for FT-516 cell therapy derived from an engineered pluripotent stem cell

First mouse kidneys grown from mouse stem cells in rats

Recida Therapeutics launches to develop lead program, RC-01

AAV9 vector encoding modified HEXB shows promise in vivo for Tay-Sachs disease

China's NMPA clears IND for bispecific antibody IBI-318

Targeting NRAS activator STK19 blocks melanocyte malignant transformation and melanoma growth

Interim data presented from first-in-human study of AT-GAA in patients with Pompe disease

Sanofi Genzyme presents long-term safety data for avalglucosidase alfa in Pompe disease

iVeena initiates phase I/IIa study of IVMED-80

Preliminary data presented from phase II study of MGTA-456 in inherited metabolic disorders

DSMB completes its third review of phase I/IIa study of VBI-1901 in recurrent GBM

Interim phase IIb data shows promising signs of clinical benefit for MDNA-55 in rGBM

New phase III study of empagliflozin assesses cardio-renal outcomes in chronic kidney disease

Moleculin's third drug candidate approved to enter clinical testing

Antidote Therapeutics to collaborate with NCI on development of ATI-1013

Ligand Pharmaceuticals enters OmniAb collaboration with Genagon Therapeutics

2-AG is a predictor of poor outcome in patients with aSAH

FDA clears IND for phase II study of Pulmazole in allergic bronchopulmonary aspergillosis

AbbVie patents lysophospholipid S1P5 receptor agonists

Phenex-FXR presents modulators of oxysterol receptors

Improved liver-targeted AAV gene therapy has long-lasting effects in Fabry disease model

Bayer and DKFZ jointly identify MAP4K1 inhibitors

Selection Biosciences divulges new 3-quinuclidone compounds

Chinese researchers disclose EGFR inhibitors

Sanofi to seek new partner for ophthalmology gene therapies SAR-422459 and SAR-421869

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