Home » Newsletters » BioWorld Science

BioWorld Science

April 10, 2019

View Archived Issues

BAY-218, a first-in-class AhR antagonist for overcoming tumor-mediated immunosuppression

How CMV blocks immune recognition

New bromophenol derivatives as specific PTP1B inhibitors for the treatment of type 2 diabetes

Mechanism underlying youthful and aging skin found in mice

Patient enrollment ongoing in phase I study of LYN-00101

First-in-human data for PLN-74809 support development of the candidate for the treatment of IPF

First patient enrolled in phase I/II study of NanoDoce for the treatment of bladder cancer

Enesi Pharma and Oxford Vaccine Group to develop plague vaccine

Researchers present new oncolytic adenovirus shRNA-based immunotherapy strategy

A*STAR describes new isoprenylcysteine carboxylmethyltransferase inhibitors

ImmuneOnco Biopharma reports discovery of novel bispecific antibody-trap, IMM-0306

Preclinical data presented for a novel cross-linking dependent 4-1BB agonist antibody, PE-0116

Next-generation of HBV CAMs presented

Zhejiang Hisun Pharmaceutical discloses mutant c-Kit/PDGFR-alpha inhibitors

New TLR7 agonists patented by Jiangsu Hengrui Medicine, Shanghai Hengrui Pharmaceutical

University of Nottingham presents CDK12/cyclin K inhibitors

Protein-arginine deiminase type-4 inhibitors discovered at Jubilant Biosys

U.S. approval for Evenity for osteoporosis in postmenopausal women at high risk for fracture

European Commission approves Lynparza for germline BRCA-mutated HER-negative advanced breast cancer

Discovery and characterization of selective AMPAR/gamma-8 negative modulators as antiepileptics

Results of phase I trial of RNA-based adjuvant CV-8102 combined with a licensed rabies vaccine

DNA-encoded monoclonal antibody prevents Zika infection in mice and nonhuman primates

GHIT Fund grant supports further development of asexual blood-stage malaria vaccine candidate

Dual kappa/delta-opioid agonist CA-1001 shows efficacy in pain models

PharmaMar announces new immuno-oncology program

Popular Stories

Today's news in brief
BioWorld
BioWorld briefs for April 17, 2026.
Biohaven reports details on discovery of BHV-2100
BioWorld Science
Transient receptor potential melastatin 3 (TRPM3) is a calcium-permeable TRP channel that is highly expressed in somatosensory neurons, including nociceptors of...
New GABA(B) receptor PAMs revealed in Addex Pharma patents
BioWorld Science
Addex Pharma SA has disclosed new GABA(B) receptor positive allosteric modulators (PAMs) potentially useful for the treatment of chronic cough, urinary...
Meta-analysis: Anti-amyloid Alzheimer’s drugs not ‘clinically meaningful’
BioWorld
The ongoing controversy over the effectiveness of anti-amyloid drugs is about to get more heated, after a review of clinical trials showed statistically...
Novel caspase-2 inhibitor shows in vivo neuroprotective effects
BioWorld Science
Caspase-2-mediated cleavage of tau at Asp314 generates a neurotoxic fragment, Δtau314, that drives early synaptic dysfunction in Alzheimer’s disease (AD) and...