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BioWorld Science

May 14, 2019

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Too much of a good thing foils heart repair

Voxelotor improves anemia in adolescents with sickle cell disease

Plasma kallikrein inhibitor VE-4840 shows preclinical potential for treating diabetic retinopathy

Long non-coding RNA CASC9 has an oncogenic role in breast cancer

IMVT-1401 demonstrates promising safety, PK and PD in healthy subjects

Flavonoid promotes pleiotropic neuroprotective effects

CAR fusion proteins targeting Strep-tagged peptides patented by Fred Hutchinson, TUM

Updated data presented from phase Ib/II study of RG-6206 in boys with DMD

WuXi Biologics describes new bispecific antibodies against EGFR and PD-1

Novel biomarkers of clinical efficacy of bevacizumab in the treatment of gastric cancer

NB-01 leads to statistically significant improvements in diabetic neuropathic pain

TRAF2 and NCK-interacting protein kinase inhibitors discovered at Silverback Therapeutics

Ajinomoto identifies new sweet receptor antagonists

Exosomal PD-L1 identified as a cancer therapeutic target

Blueprint Medicines discloses activin receptor type-1 inhibitors

ORIC Pharmaceuticals initiates phase Ib study of ORIC-101 in advanced solid tumors

Promising topline results announced from phase IIb study of seltorexant in major depressive disorder

Oncolytic adenovirus with specificity for ARMS cells presented

FDA approves Eylea to treat all stages of diabetic retinopathy

NIH grant supports Ichor's development of antibodies against hantavirus infections

DSMB 36-month review of phase III RESOLVE-IT trial of elafibranor in NASH recommends continuation

Mitochondrial DNA polymorphism linked to infant bronchopulmonary dysplasia

P-MUC1C-101 shows robust antitumor effects in orthotopic breast tumor model

Sevuparin fails to show meaningful benefit in phase II trial to manage VOC in sickle cell disease

Confirmatory phase III trial of dasiglucagon in severe hypoglycemia meets primary endpoint

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