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BioWorld Science

May 28, 2019

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Optimization of quinazoline-based BET inhibitors for cancer and inflammatory diseases

Results of phase IIb trial of topical PAC-14028, a TRPV1 antagonist, in atopic dermatitis

Knopp Biosciences presents positive preclinical data for neonatal epilepsy drug candidate KB-3061

Crystal healing -- it's science!

Targeting cancer stem cell metabolism

Circulating exosomes may serve as biomarker of stem cell effectiveness

In vitro proof of concept for Immatics' TCER immunotherapy

Novel PI3Kdelta-selective inhibitors based on 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-ones

ALK2 inhibitors prolong survival in xenograft model of ACVR1 mutant diffuse intrinsic pontine glioma

JNJ-28583113, a novel specific TRPM2 antagonist, shows promising in vitro activity

Rheacell begins phase I/IIa study of allogeneic ABCB5-positive limbal stem cells for LSCD

Arena opens enrollment in phase III study of etrasimod for ulcerative colitis

Innate enrolling in phase II study of IPH-4102 in advanced T-cell lymphomas

Spero studies tebipenem pivoxil hydrobromide in phase III for cUTI or acute pyelonephritis

First-in-human results from HEPAVAC-101 study presented

Ansun studies DAS-181 in phase III for lower tract PIV infections in immunocompromised patients

Newron delays start of phase II/III studies of evenamide for schizophrenia

Massachusetts Institute of Technology patents MYC inhibitors

FLX Bio presents new USP7 inhibitors

Bayer discloses PE inhibitors

New PRMT5 inhibitors patented by Merck and collaborators

Paradigm reports new real-world data on iPPS in knee osteoarthritis

Medshine Discovery divulges IAP inhibitors

FDA approves sNDA for Vraylar for bipolar depression

Phase III cohort of valoctocogene roxaparvovec meets criteria for regulatory review

Calidi collaborates with NIH to study therapeutic potential of oncolytic viruses delivered by MSCs

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