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BioWorld Science

July 25, 2019

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Tipping the scales against p53 mutations

Blocking neurogenesis ineffective against chronic seizures

Oral anti-CD3 (OKT-3) results in immunologic changes in patients with ulcerative colitis

Regeneron studies REGN-5678 with cemiplimab in metastatic castration-resistant prostate cancer

Merck & Co. presents clinical data for MK-8591 in patients with HIV-1 infection

First subject enrolled in phase III ONSET-2 study of OC-01 nasal spray

Patient enrollment ongoing in phase I study of SEL-120 in patients with AML or HR-MDS

Synthorx initiates first-in-human HAMMER study of THOR-707

SRI-011381 is neuroprotective and improves cognition in vivo

Preliminary phase I data for the long-acting HIV capsid inhibitor GS-6207

Novel p53 gene therapy increases efficacy of cabazitaxel in prostate carcinoma models

Orion's OB-002 shown to be more potent than maraviroc in a model of HIV infection

Brain drain may hold key to treating neurodegenerative diseases

King Saud University discovers new calcium channel blockers

Wuxi Advant Biotechnology identifies NUDT1 inhibitors

New CSF-1 receptor inhibitors described by Medshine Discovery

Guangzhou Henovcom Bioscience patents MAP3K5 inhibitors

HitGen describes stimulator of interferon genes protein agonists

CR3 is a potential therapeutic target for treating Neisseria gonorrhoeae infection

Exscientia announces collaboration with Rallybio for development of rare disease therapeutics

Daewoong initiates phase II study of DWP-16001 in type 2 diabetes

FDA approves Baqsimi to treat severe hypoglycemia

CEPI funding to support Valneva's late-stage development of chikungunya vaccine

Scynexis reaches SPA agreement with FDA on phase III study of ibrexafungerp to prevent recurrent VVC

BioHaven opens enrollment in phase III study of BHV-3241 for multiple system atrophy

REGENXBIO adds new HAE program to pipeline, collaborates with Neurimmune

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