Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 18, 2019

View Archived Issues

Roche presents first-in-human data for RO-7062931

HPN-328 targeting DLL3 shows preclinical efficacy and safety for immunotherapy in SCLC

New Smo antagonist shows antitumor activity in medulloblastoma and cholangiocarcinoma animal models

New PEGylated IL-2 with improved pharmacologic properties specifically activates and expands Tregs

Anchiano discontinues phase II Codex study of inodiftagene vixteplasmid in NMIBC

Positive results presented from second phase III psoriasis study of bimekizumab

Results presented from proof-of-concept phase I study of cenerimod

First-in-human data presented for tetrameric bispecific antibody AK-104

DRA inhibitors synthesized for cystic fibrosis-related nephrolithiasis

Gut bacteria can drive heart autoimmunity

Succinate identified as novel cancer therapy target

Sparsentan does not appear to have a negative effect on quality of life in FSGS patients

First-in-human data for novel platelet glycoprotein IIb/IIIa inhibitor RUC-4 in patients with STEMI

Institute for Translational Vaccinology tests RSV vaccine in phase I study

Japanese researchers patent TRPC3 and TRPC6 antagonists

Nippon Chemiphar discloses xanthine oxidase inhibitors

Innate Tumor Immunity identifies NLRP3 agonists

Korean investigators disclose mTORC1 inhibitors

New SCD1 and SCD5 inhibitors presented by Yumanity Therapeutics

Phase I trial studies Rocket's hematopoietic cell-based gene therapy for pyruvate kinase deficiency

Shanghai De Novo studies DN-1508052-01 in phase I for advanced solid tumors

FDA approves Adakveo to reduce vaso-occlusive crises in patients with sickle cell disease

Popular Stories

Today's news in brief
BioWorld
BioWorld briefs for March 10, 2026.
Cas and effect: Merck’s phase III ripples HIF-2α space
BioWorld
Oddsmakers wasted no time figuring the market chances after Merck & Co. Inc. rolled out data from the phase III Litespark-011 study testing its oral...
Brain’s hidden tau-clearing pathway uncovered
BioWorld Science
Researchers at INSERM and collaborators have identified hypothalamic tanycytes as mediators of tau clearance and shown that their structural and genetic...
News in brief
BioWorld Asia
BioWorld Asia briefs for March 10, 2026
MSD synthesizes α-synuclein PET agents
BioWorld Science
Merck Sharp & Dohme LLC (MSD) has prepared and tested new positron emission tomography (PET) agents for binding and imaging α-synuclein (SNCA) for the diagnosis...