Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 20, 2019

View Archived Issues

Integrated stress response backfires in Down syndrome

Researchers create new rat and pig models of cystic fibrosis

Novel potent OXE receptor antagonists with prolonged plasma lifetime for eosinophilic diseases

Positive data presented for WP-1220 in patients with CTCL

Novel prostate cancer bone metastasis model in humanized mice

Seviprotimut-L demonstrates safety and efficacy in part B1 of MAVIS phase III study

RQ-00490721 prevents cardiac dysfunction in mouse model of heart failure

Haplodeficiency disrupts microglial responses in AD models

Celldex begins phase Ia study with KIT inhibitor CDX-0159

DWP-212525, a next-generation therapeutic for autoimmune diseases

COR-001 suppresses hsCRP in patients with chronic kidney disease

Phase III study of vericiguat in worsening chronic heart failure meets primary endpoint

Phase III dosing defined for lixivaptan in autosomal dominant polycystic kidney disease

Scholar Rock reports preliminary PK and PD data from phase II study of SRK-015 in SMA

New ASK1/TAK1 dual kinase inhibitor for treating NASH presented

Shanghai Longwood Biopharmaceuticals divulges compounds for HBV

Preliminary clinical data on CRISPR/Cas9 gene-editing therapy CTX-001 in severe hemoglobinopathies

Enanta Pharmaceuticals patents MAP3K5 inhibitors

Adenosine A2A receptor antagonist DZD-2269 overcomes adenosine-induced immunosuppression

ORIC Pharmaceuticals presents CD73 inhibitors

Amgen identifies novel apelin receptor agonists

REVOLUTION Medicines patents mTOR inhibitors

New phase III trial in Japan studies KW-3357 to treat early-onset pre-eclampsia

Popular Stories

Today's news in brief
BioWorld
BioWorld briefs for Jan 26, 2025.
Today's news in brief
BioWorld MedTech
BioWorld MedTech briefs for Jan. 27, 2026.
Biallelic variants in COX18 identified as cause of Charcot-Marie-Tooth disease
BioWorld Science
Charcot-Marie-Tooth (CMT) disease is a group of clinically and genetically heterogeneous sensorimotor peripheral neuropathies. It is the most frequent inherited...
Brain-derived tau in blood predicts stroke severity and outcome
BioWorld Science
Brain-derived tau, a protein that is exclusive to the brain and detectable in the blood, could serve as an indicator of brain damage after an ischemic stroke. The...
Muted and missing M&As: JPM deals absent in 2026
BioWorld
For years, the J.P. Morgan Healthcare Conference (JPM) kicked off with splashy headlines of major M&A activity among biopharma companies, but in 2026, the hype...